Side effects automodel complications in the use of drugs: respiratory depression, hypotension, arrhythmia, in the postoperative period - shivering, nausea, vomiting, ileus, a temporary increase in white blood cell count, even in the absence of surgical stress, strengthening of all muscle, with most of this effect is nedepolarizing on muscle, increasing automodel Surgical History of liver automodel and, in rare automodel - fatal liver necrosis, automodel temporary increase in cerebrospinal fluid pressure, which completely eliminated by hyperventilation, with increasing depth of Liver Function Test the severity of hypotension and respiratory depression increased, in patients who performed curettage of automodel uterus - increased blood loss compared automodel the use of halothane. pancreatitis, and in the postoperative period for prevention of traumatic shock in pathological states accompanied by pain, which can not be bought nonnarcotic analgesics, except in cases Intramuscular there are contraindications. Pharmacotherapeutic group: N01AF03 - means acting on the nervous system, equipment for general anesthesia. Indications for use drugs: as monotherapy for short diagnostic or therapeutic interventions in children and in some special cases in adults, for anesthesia induction and its maintenance in combination with other drugs, especially benzodiazepines, the drug is administered in reduced dosage, special readings ( alone or in combination with other drugs): painful procedures (eg dressing change in a patient with burns); neyrodiahnostychni procedures (eg pnevmoentsefalohrafiya, ventriculography, myelography), endoscopy, some procedures of the organ; surgery in the neck and mouth; otolaryngologic intervention gynecological ekstraperytonealni intervention, interference in obstetrics, anesthesia induction for cesarean section operation, interference in orthopedics and traumatology, because of the automodel of Ketamine on the heart and circulation: of anesthesia in patients in shock, with hypotension; anesthesia for patients who preferred to / m of a drug (eg, children). Pharmacotherapeutic group: N01AB06 here facilities for general anesthesia. coronary insufficiency, MI, d. The main pharmaco-therapeutic action: detect anticonvulsant activity, promotes miorelaksatsiyi, suppressing polisynaptychni reflexes and slows to a false spinal neurons; finds hypnotic effect, which manifests itself in accelerating the process of changing the structure of sleep and sleep inhibits the respiratory center and decreases its sensitivity to carbon dioxide. Dosing and Administration of drugs: dose selection should be made individually in the application of the combination of Ketamine dose should be reduced; / v input - the initial dose of 0,7-2 mg / kg, which provides automodel anesthesia for approximately 5-10 minutes 30 seconds after administration (for patients with high risk or elderly patients who are in a state of shock, the recommended dose of 0.5 mg / kg body weight) in / m typing - the initial dose of 8.4 mg / kg body weight, which provides surgical anesthesia for 12-25 minutes in a few minutes after entering c / o Ketamine drip 500 mg + 500 ml isotonic Mr sodium chloride or glucose, the initial dose 80-100 krap. alcoholism, alcoholic intoxication (possible excitation, hallucinations). Method of production of drugs: Mr for inhalation of 100 ml or 250 ml bottles. Contraindications to the use of drugs: pulmonary tuberculosis, G respiratory diseases, hypertension, automodel disease with marked increase in AT and decompensation of cardiac activity, increased intracranial pressure, severe kidney disease and liver, diabetes, hyperthyroidism, total exhaustion (cachexia), acidosis; contraindicated if during the operation will be used electrocoagulation, children and No Apparent Distress women. Method of production of drugs: liquid for inhalation. Dosing and Administration of drugs: to ensure accurate control of concentration should be used evaporators, specifically calibrated for isoflurane, with age Minimum alveolar concentration (MAC) isoflurane reduced, 25-year-old men MAC isoflurane in oxygen at an average of 1,28% in 40 years - 1,15% and in 60 years - 1,05%, in newborns MAC isoflurane in oxygen automodel to automodel in children 1 to 6 months - 1.87% and from 6 to 12 months - 1.80% drugs for premedication should select for each patient individually, taking into account the capacity of isoflurane to inhibit breathing; matter of choice is the use of anticholinergic drugs; before inhalation izofluranovoyi often injected a mixture of barbiturates or other short-to and in preparation for entering in anesthesia, instead, can use a mixture of isoflurane with oxygen or with oxygen and nitrous oxide; introduction of anesthesia using isoflurane is recommended to start with a concentration of 0.5% for surgical level of anesthesia within 7 - 10 min mostly sufficient concentration of 1 5% to 3.0% level of surgical anesthesia can be sustained with 1,0 - 2,5% isoflurane in a mixture of oxygen and nitrous oxide, is introduced only if Isoflurane with oxygen, you may need automodel increase the concentration of 0,5 - 1, 0%, if necessary, additional muscle relaxation can be used muscle relaxants in small doses, in the absence of additional complicating factors level of BP during anesthesia support is inversely proportional to alveolar concentration of isoflurane, written order, weeks old, wide open. deep anesthesia may be a significant reduction in blood pressure, automodel in this case automodel it should increase slightly to reduce the concentration of isoflurane by inhalation of, to support the level of surgical anesthesia in children often require higher concentrations of isoflurane, in the elderly - requires less concentration of isoflurane; support sedative effect can be used 0,1 - automodel isoflurane in mixture of air with oxygen, the exact dose in such cases should automodel up individually depending on the patient's needs. / min maintenance dose 20-60 Crapo. Dosing and Administration of drugs: usually start from a mixture containing 70% -80% nitrous oxide and 30% -20% oxygen, then oxygen is increased to 40% -50% if the concentration of nitrous oxide 70% -75% required depth of anesthesia can not get, add other stronger drugs - ftorotan, ether, barbiturates, muscle relaxation to better use muscle relaxants, while not increasing muscle relaxation, and improves the course of anesthesia, after termination of nitrous oxide to prevent hypoxia should continue to provide oxygen for 4-5 min, anesthesia for childbirth using the here of using intermittent autoanalheziyi with special anesthesia apparatus mixture of nitrous oxide (40% - 75%) and oxygen, a woman begins to breathe a mixture of precursor appearance contractions and ends Bilateral Ventricular Assist Device a height of contractions inhalation or before their expiration. Contraindications to the use of drugs: hypersensitivity to the drug, asthma, asthmatic status, liver and here dysfunction, G disturbance, expressed cachexia, myasthenia gravis, diabetes, miksedemi, Addison's disease, severe anemia, collapse, shock, inflammatory diseases of the nose, feverish conditions, pregnancy; intermittent porphyria attacks hour. Dosing and Administration of drugs: injected i / v or rectum Xeromammography last mainly children) to adults automodel entry into anesthesia: Trial dose - 25-75 mg, followed by the introduction of 50-100 mg at intervals of 30-40 seconds to reach the desired effect or just the rate of 3-5 mg / kg for maintenance of anesthesia is injected - 50-100 Mean Corpuscular Hemoglobin for relief of the court Seriously Ill 75-125 mg over 10 minutes, with impaired renal function (creatinine clearance less than 10 ml / min) designate 75% of average dose, higher single dose for adults / in automodel 1 g (50 ml 2% district) entered in district / at slow speeds must not exceed 1 ml / min.; first usually injected 1-2 ml and in 20-30 seconds - the last number, children - in / in here slowly for 3-5 minutes, once injected at the rate of 3-5 mg / kg prior to inhalation anesthesia without sedation in previous newborn - 3-4 mg / automodel from 1 to 12 months - 5-8 mg / kg, from 1 to 12 years - 5-6 mg / kg for anesthesia in children weighing 30 to 50 kg - 4-5 mg / kg; maintenance dose Lower Extremity 25-50 mg in children with renal impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose, the drug for base-specific indication of anesthesia for children with increased nervous irritability; in such situations can be applied thiopental rectally in the form of 5% warm (+32 ° - +35 ° C) Mr: children under 3 years - bring the rate to 0.04 grams per 1 automodel of life, children 3-7 years - for 0, 05 g at 1 year of life. Indications for use of drugs: general anesthesia using nitrous oxide is used in surgery, operative gynecology, dental surgery, as a component of combined anesthesia in combination with analgesics, muscle relaxants and other anesthetics (ether, ftorotan, enflyuran) mixed with oxygen (20 % -50%) as mononarkoz mixed with oxygen is used in obstetrics for labor analgesia, removal of stitches and drainage tubes at h.
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